Volume 9, Issue 13

The Pancreas, Malnutrition, and CFTR Modulators

In this issue:

Pancreatic insufficiency. In children with CF, it’s been associated with delayed development and increased odds of developing severe lung disease. How can it be more accurately diagnosed? And what does the evidence say about the effects of treatment with CFTR modulators?

That’s what we explore in this case-based podcast, with Dr. Vikesh Singh, Associate Professor of Medicine and Director of the Pancreatitis Center at Johns Hopkins Medical Institutions. 

Learning objectives:

  • Explain the physiological mechanisms that result in malnutrition in patients with cystic fibrosis. 
  • Describe the impact of CFTR modulators on parameters of nutrition, exocrine function and recurrent acute pancreatitis in patients with cystic fibrosis. 


Vikesh K. Singh, MD, MSc
Vikesh K. Singh, MD, MSc

Associate Professor of Medicine, Division of Gastroenterology, Department of Medicine 
Johns Hopkins University School of Medicine 
Director of Endoscopy 
Johns Hopkins Hospital 
Director, Pancreatitis Center 
Medical Director, Pancreatic Islet Autotransplantation Program 
Johns Hopkins Medical Institutions 
Baltimore, MD

Program Directors:

Noah Lechtzin, MD, MHA

Director, Adult Cystic Fibrosis Program
Associate Professor of Medicine
Johns Hopkins University School of Medicine
Baltimore, MD

Peter J. Mogayzel, Jr., MD, PhD

Professor of Pediatrics
Director, Cystic Fibrosis Center
Johns Hopkins University School of Medicine
Baltimore, MD

Donna Peeler, RN

Clinical Nurse 
Pediatric Clinic Coordinator 
Johns Hopkins Cystic Fibrosis Center 
Baltimore, MD

Length of activity:

0.5 hour Physicians
0.5 contact hour Nurses

Launch date: March 31, 2021
Expiration date: March 30, 2023