Volume 1, Issue 2

In Clinical Practice: Overcoming Patient Barriers to PrEP

Editor's note:

In this podcast, Guest Author Dr. Douglas Krakower notes that “people who are living with HIV and use ART are at much lower risk of transmitting the virus to their partners.” Dr. Krakower has advised us this statement has been further bolstered by recently published evidence supporting the “U=U” (Undetectable viral levels equals Untransmittable virus) concept. Data reinforcing the decreased risk of viral transmission with ART treatment include 2019 studies published in The Lancet, JAMA, and Lancet HIV (among other sources). 

In this issue:

PrEP — pre-exposure prophylaxis to prevent HIV transmission — is safe, it’s effective, and it’s significantly underused in the U.S.  One key barrier to increased PrEP use is a lack of awareness and acceptance among the patient populations most at-risk for new HIV infection.

In this podcast, Dr. Douglas Krakower from Harvard Medical School takes us into the exam room to translate the new information in his Newsletter Issue into clinical practice.

Learning objectives:

  • Summarize the priority populations where PrEP implementation is likely to have the greatest impact.
  • Identify how to help at-risk patients with limited awareness of PrEP make informed decisions about accepting PrEP.
  • Describe an unbiased approach to prescribing decisions about HIV pre-exposure prophylaxis.


Douglas Krakower, MD
Douglas Krakower, MD

Assistant Professor of Medicine
Harvard Medical School
Staff Physician
Division of Infectious Diseases
Beth Israel Deaconess Medical Center
Boston, MA

Program Directors:

Joyce King, MD

Assistant Professor
Georgetown University School of Medicine
Director, Inpatient Medicine
Family Medicine Residency Program
Medstar Franklin Square Hospital
Baltimore, MD

Glenn Treisman, MD, PhD

Eugene Meyer III Professor of Psychiatry and Medicine
Director, AIDS Psychiatry Services
Co-Director, Chronic Pain Treatment Program
Johns Hopkins University School of Medicine
Baltimore, MD

Length of activity:

0.5 hour Physicians
0.5 contact hour Nurses

Launch date: June 15, 2019
Expiration date: June 14, 2021