Volume 9, Issue 6

CFTR, Growth & Liver Disease: A Clinical Perspective

In this issue:

Where, beyond the lungs, do CFTR modulators provide beneficial effects? Can treatment promote growth in height and BMI? What’s known about CFTR modulator effects on cystic fibrosis-associated liver disease?  

In this eCysticFibrosis Review podcast, Drs. Darla Shores and Anna Reed from the THRIVE Pediatric Intestinal Rehabilitation Center in the Division of Gastroenterology, Hepatology, and Nutrition at the Johns Hopkins Children's Center take us to the clinic to answer these and other questions crucial to the health of our patients with cystic fibrosis. 

Learning objectives:

  • Describe what’s currently known about how CFTR modulators affect growth.
  • Explain how CFTR modulators affect liver tests and CF liver disease.


Darla Shores, MD, PhD
Darla Shores, MD, PhD

Assistant Professor of Pediatrics 
Associate Fellowship Director, Pediatric Gastroenterology 
Medical Co-Director, THRIVE Pediatric Intestinal Rehabilitation Center 
Division of Gastroenterology, Hepatology, and Nutrition 
Johns Hopkins Children's Center 
Baltimore, MD



Anna Reed, MD, MPH
Anna Reed, MD, MPH

Johns Hopkins Division of Gastroenterology, Hepatology, and Nutrition 
Johns Hopkins Children's Center 
Baltimore, MD

Program Directors:

Noah Lechtzin, MD, MHA

Director, Adult Cystic Fibrosis Program
Associate Professor of Medicine
Johns Hopkins University School of Medicine
Baltimore, MD

Peter J. Mogayzel, Jr., MD, PhD

Professor of Pediatrics
Director, Cystic Fibrosis Center
Johns Hopkins University School of Medicine
Baltimore, MD

Donna Peeler, RN

Clinical Nurse 
Pediatric Clinic Coordinator 
Johns Hopkins Cystic Fibrosis Center 
Baltimore, MD

Length of activity:

0.5 hour Physicians
0.5 contact hour Nurses

Launch date: August 3, 2020
Expiration date: August 2, 2022