Volume 7, Issue 10

Weight Gain in PLWH: A Clinical Concern

In this issue:

Most people living with HIV gain weight when initiating ART. For some, the weight gain signifies a “return to health”; for others, the additional weight can be clinically significant and may be strongly associated with an increased risk of metabolic abnormalities. What causes this weight gain? How can patients most at risk for weight-related comorbidities be identified? 

Join us as we discuss these and other issues with Dr. Todd Brown, Professor of Medicine and Epidemiology at Johns Hopkins University, in this eHIV Review podcast. 

Learning objectives:

  • Describe medication selection for ART initiation in patients for whom potential weight gain should be minimized. 
  • Discuss the evidence about whether the weight gain that has been associated with ART agents is actually caused by those agents. 


Todd Brown, MD, PhD
Todd Brown, MD, PhD

Professor of Medicine and Epidemiology
Johns Hopkins University
Baltimore, MD

Program Directors:

Justin Alves, RN, FNP-BC, ACRN, CARN, CNE

Nurse Educator
Boston Medical Center
Boston, MA

Matthew Spinelli, MD, MAS

Assistant Professor
HIV, ID, and Global Medicine
Zuckerberg San Francisco General Hospital
San Francisco, California

Ethel D. Weld, MD, PhD

Assistant Professor of Medicine and Pharmacology and Molecular Sciences
Division of Infectious Diseases
Division of Clinical Pharmacology
Johns Hopkins School of Medicine
Baltimore, Maryland

Length of activity:

0.5 hour Physicians
0.5 contact hour Nurses

Launch date: September 7, 2022
Expiration date: September 6, 2024